Characteristics of Giant Viruses: Achantamoeba polyphaga Mimivirus, Pandoravirus and Tupanvirus: A Review of the Literature
DOI:
https://doi.org/10.63142/ijeti.v1i1.241Keywords:
Giant Virus, Mimivirus, Pandoravirus, TupanvirusAbstract
'Giant viruses' are viruses that have a genome of >200,000 bp and have been shown to infect eukaryotic organisms such as algae and protists. Giant viruses viruses have unique characteristics in addition to being very large in size, these viruses have a complex genome structure so that they are able to reproduce independently in the host cell. independently in the host cell. Some of these viruses are Achantamoeba polyphaga Mimivirus, Pandoravirus and Tupanvirus. This review aims to summarize the research that has been done on the giant viruses that have been have been discovered. Methods used in writing this article were analyzed through searches on scientific databases such as PubMed, ScienceDirect and Google Scholar.
References
C. M. L. a. J. M. C. Abergel, "Abergel, Chantal, Matthieu LegeThe Rapidly Expanding Universe of Giant Viruses: Mimivirus, Pandoravirus, Pithovirus and Mollivirus.," Abergel, Chantal, Matthieu Legendre, and Jean Michel Claverie. “The Rapidly Expanding UnFEMS Microbiology Reviews 39, no. 6 (2015): 779–96., vol. 39, no. 6, pp. 779-796, 2015.
J. S. F. P. D. L. C. S. G. M. A. P. V. B. P. C. B. L. S. a. E. G. K. Abrahão, "Acanthamoeba Polyphaga Mimivirus and Other Giant Viruses: An Open Field to Outstanding Discoveries.," Vorology Journal, vol. 11, no. 1, pp. 1-12, 2014.
P. J. D. A. G. M. d. F. A. L. B. A. C. L. F. A. O. C. D. d. A. S. e. a. Boratto, "Acanthamoeba Polyphaga Mimivirus Prevents Amoebal Encystment-Mediating Serine Proteinase Expression and Circumvents Cell Encystment," Journal of Virology, vol. 89, no. 5, pp. 2962-2965, 2015.
C. S. G. E. M. M. S. J. Wilhelm SW, "Standing on the Shoulders of Giant Viruses: Five Lessons Learned about Large Viruses Infecting Small Eukaryotes and the Opportunities They Create," Plos pathogens , vol. 12, no. 8, pp. 1-5, 2016.
P. B. L. S. A. L. G. C.-A. a. D. R. Colson, "Mimivirus: Leading the Way in the Discovery of Giant Viruses of Amoebae.," Nature Reviews Microbiology , vol. 15, no. 4, pp. 243-254, 2017.
E. E. P. E. M. N. P. A. a. K. I. P. Kalafati, "Mimiviruses: Giant Viruses with Novel and Intriguing Features (Review).," Molecular Medicine Reports , vol. 25, no. 6, pp. 1-6, 2022.
D. J. P. B. S. H. P. D. E. C. S. A. a. B. L. S. Sahmi-Bounsiar, "Generation of Infectious Mimivirus Virions Through Inoculation of Viral DNA Within Acanthamoeba Castellanii Shows Involvement of Five Proteins, Essentially Uncharacterized," Frontiers in Microbiology, vol. 12, pp. 1-10, 2021.
L. S. T. L. S. M. F. d. F. E. K. ,. B. L. S. &. J. S. (. Graziele Oliveira, "Tupanvirus-infected Amoebas Are Induced To Aggregate With Uninfected Cells Promoting ViralDissemination.," Dissemination, vol. 9, p. 183, 2019.
F.-S. Y. M. E. Mutsaf Y, "Infection cycles of large DNA viruses: emerging themes and underlying questions.," Virology 466–467:3–14., vol. 466, pp. 3-14, 2014.
S. M. P. C. B. L. S. J. S. A. Rodrigo Araújo Lima Rodrigues, "Tupanvirus," Family Mimiviridae. 164:325–331., vol. 164, p. 331, 2019.
F. C. Cheng Sun., "DNA transposons have colonized the genome of the giant virus Pandoravirus salinus.," BMC Biology Part of Springer Nature;13(38)., vol. 13, no. 38, 2015.
B. P. Andrade. A.S., "New Isolates of Pandoraviruses: Contribution to the Study of Replication Cycle Steps.," American Society For Microbiology; Journal of Virology, vol. 93, no. 5, 2019.
L. M.-M. Philippe. N., "PhilipPandoraviruses: amoeba viruses with genomes up to 2.5 Mb reaching that of parasitic eukaryotes.," Sience. , vol. 341, pp. 281-286, 2013.
G. E. Antwerpen M. H., "Whole-genome sequencing of a pandoravirus isolated from keratitis-inducing acanthamoeba.," Genome Announc., vol. 3, pp. 136-15, 2015.
A. J. Aherfi S, " A Large Open Pangenome and a Small Core Genome for Giant Pandoraviruses," Front Microbial, vol. 9, p. 1486, 2018.
P. J., "Newly Found Pandoraviruses Hint at a Fourth Branch of Life," Nature, 2013.
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